1042385-75-0
1042385-75-0 structure
- Name: PF-00299804
- Chemical Name: (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide,hydrate
- CAS Number: 1042385-75-0
- Molecular Formula: C24H27ClFN5O3
- Molecular Weight: 487.95
- Catalog: Signaling Pathways JAK/STAT Signaling EGFR
- Create Date: 2017-06-19 08:42:18
- Modify Date: 2024-01-09 20:48:08
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Dacomitinib (PF-00299804) hydrate is an orally active, irreversible pan-ErbB inhibitor. Dacomitinib hydrate can be used in the research of cancers such as metastatic non-small cell lung cancer (NSCLC)[1].
| Name | (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide,hydrate |
|---|---|
| Synonyms |
(2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl}-4-(1-piperidinyl)-2-butenamide hydrate (1:1)
Dacomitinib [USAN:INN] 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-, (2E)-, hydrate (1:1) (2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide, hydrate (1:1) UNII-5092U85G58 2-Butenamide,N-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxy-6-quinazolinyl)-4-(1-piperidinyl)-,hydrate (1:1),(2E) Dacomitinib dacomitinib hydrate Dacomitinib hydrate (JAN) (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide monohydrate Dacomitinib monohydrate (2E)-N-(4-(3-Chloro-4-fluorophenyl)amino)7-methoxyquinazolin-6-yl)4-(piperidin-1-yl)but-2-enamide monohydrate PF-00299804 |
| Description | Dacomitinib (PF-00299804) hydrate is an orally active, irreversible pan-ErbB inhibitor. Dacomitinib hydrate can be used in the research of cancers such as metastatic non-small cell lung cancer (NSCLC)[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C24H27ClFN5O3 |
|---|---|
| Molecular Weight | 487.95 |
| Exact Mass | 487.178650 |
| PSA | 92.10000 |
| LogP | 5.75120 |
| Hazard Codes | Xi |
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