34104-67-1
34104-67-1 structure
- Name: Haloperidol Metabolite II
- Chemical Name: Reduced Haloperidol
- CAS Number: 34104-67-1
- Molecular Formula: C21H25ClFNO2
- Molecular Weight: 377.88000
- Catalog: analytical chemistry Standard Forensic and veterinary standards
- Create Date: 2016-06-20 19:38:03
- Modify Date: 2025-08-25 15:51:21
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Reduced haloperidol is an active metabolite of haloperidol formed via reduction of haloperidol by ketone reductase. Reduced haloperidol inhibits radioligand binding to sigma-1 and dopamine D2 receptors and stimulates brain-derived neurotrophic factor (BDNF) secretion from CCF-SSTG1 and U87MG astrocytic glial cells. It also inhibits norepinephrine, dopamine, and serotonin (5-HT) reuptake.
| Name | Reduced Haloperidol |
|---|---|
| Synonyms | Haloperidol metabolite II |
| Density | 1.247g/cm3 |
|---|---|
| Boiling Point | 531.2ºC at 760 mmHg |
| Melting Point | 125-127°C |
| Molecular Formula | C21H25ClFNO2 |
| Molecular Weight | 377.88000 |
| Flash Point | 275.1ºC |
| Exact Mass | 377.15600 |
| PSA | 43.70000 |
| LogP | 4.21420 |
| Appearance | white |
| Index of Refraction | 1.589 |
| Storage condition | Refrigerator |
| Water Solubility | DMSO: soluble10mg/mL |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933399090 |
|
~88%
34104-67-1 |
| Literature: Yang, Shi-Bing; Major, Felix; Tietze, Lutz F.; Rupnik, Marjan Journal of Pharmacology and Experimental Therapeutics, 2005 , vol. 315, # 1 p. 352 - 362 |
|
~%
34104-67-1 |
| Literature: US3936468 A1, ; |
| Precursor 2 | |
|---|---|
| DownStream 1 | |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |