Name | (S)-flurbiprofen |
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Synonyms |
[1,1'-biphenyl]-4-acetic acid, 2-fluoro-a-methyl-
2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetic acid 2-FLUORO-α-METHYL-4-BIPHENYLACETIC ACID 2-(2-Fluoro-4-biphenylyl)propanoic acid Froben Anside EINECS 257-263-1 d-Flurbiprofen [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl- Stayban Esflurbiprofen MFCD00866152 (S)-Flurbiprofen 2-(2-fluorobiphenyl-4-yl)propanoic acid Ocufen Ansaid (±)-Flurbiprofen 2-(2-fluoro-4-biphenylyl)propionic acid Zepolas Adfeed rac-Flurbiprofen tarenflurbil Flurbiprofen |
Description | (S)-Flurbiprofen is an active enantiomer of Flurbiprofen, with IC50 values of 0.48 μM and 0.47 μM for COX-1 and COX-2, respectively[1]. |
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Related Catalog | |
Target |
COX-1:0.48 μM (IC50) COX-2:0.47 μM (IC50) |
In Vitro | (S)-Flurbiprofen (10–7 M) results in a total suppression of basal and stimulated PGE2 release in rat skin[2]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 376.2±30.0 °C at 760 mmHg |
Melting Point | 109-110ºC(lit.) |
Molecular Formula | C15H13FO2 |
Molecular Weight | 244.261 |
Flash Point | 181.3±24.6 °C |
Exact Mass | 244.089951 |
PSA | 37.30000 |
LogP | 4.11 |
Vapour Pressure | 0.0±0.9 mmHg at 25°C |
Index of Refraction | 1.568 |
Hazard Codes | T |
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Risk Phrases | R25 |
Safety Phrases | 36/37/39-45 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |