24192-64-1
24192-64-1 structure
- Name: epiyangambin
- Chemical Name: 3,6-bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan
- CAS Number: 24192-64-1
- Molecular Formula: C24H30O8
- Molecular Weight: 446.49
- Catalog: Natural product Lignans
- Create Date: 2017-08-12 23:26:07
- Modify Date: 2025-08-27 00:52:08
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Epiyangambin is a competitive platelet activating factor receptor (PAF) antagonist that dose-dependently inhibits PAF-induced platelet aggregation. Epiyangambin also inhibits the growth of human colon cancer cells (SW480 cells)[1][2].
| Name | 3,6-bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan |
|---|---|
| Synonyms |
syringaresinol dimethyl ether
lirioresinol B dimethyl ether epiyangambin |
| Description | Epiyangambin is a competitive platelet activating factor receptor (PAF) antagonist that dose-dependently inhibits PAF-induced platelet aggregation. Epiyangambin also inhibits the growth of human colon cancer cells (SW480 cells)[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Epiyangambin (0-25 µM; 24 h) 以剂量依赖性方式抑制 SW480 细胞的生长[1]。 Cell Viability Assay[1] Cell Line: SW480 cells Concentration: 0-25 µM Incubation Time: 24 h Result: Caused reductions in cell number in a dose-dependent manner. |
| In Vivo | Epiyangambin (20 mg/kg) 显著抑制血小板激活因子受体 (PAF) 诱导的大鼠血小板减少症[2]。 |
| References |
| Density | 1.183g/cm3 |
|---|---|
| Boiling Point | 556.1ºC at 760 mmHg |
| Melting Point | 112-114℃ |
| Molecular Formula | C24H30O8 |
| Molecular Weight | 446.49 |
| Flash Point | 221.1ºC |
| Exact Mass | 446.19400 |
| PSA | 73.84000 |
| LogP | 3.81340 |
| Vapour Pressure | 7.78E-12mmHg at 25°C |
| Index of Refraction | 1.537 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2932999099 |
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |