708-53-2

708-53-2 structure

Name: 2',3'-Dihydroxy-4'-methoxyacetophenone
Chemical Name: 1-(2,3-dihydroxy-4-methoxyphenyl)ethanone
CAS Number: 708-53-2
Molecular Formula: C₉H₁₀O₄
Molecular Weight: 182.173
Catalog: Natural product Phenols
Create Date: 2018-10-20 12:17:54
Modify Date: 2024-01-04 19:38:36
2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from Cynenchum paniculatum. 2,3-Dihydroxy-4-methoxyacetophenone improves cognitive function and may has the potential for the treatment of Alzheimer's disease research[1].

Name	1-(2,3-dihydroxy-4-methoxyphenyl)ethanone
Synonyms	2,3-Dihydroxy-4-methoxy-acetophenon Gallacetophenone-4'-methyl Ether 2,3-dihydroxy-4-methoxyacetophenone 1-acetyl-2,3-dihydroxy-4-methoxybenzene Ethanone, 1-(2,3-dihydroxy-4-methoxyphenyl)- MFCD00180772 1-(2,3-Dihydroxy-4-methoxyphenyl)ethanone 1-(2,3-DIHYDROXY-4-METHOXYPHENYL)-ETHANONE

Description	2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from Cynenchum paniculatum. 2,3-Dihydroxy-4-methoxyacetophenone improves cognitive function and may has the potential for the treatment of Alzheimer's disease research[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	2,3-Dihydroxy-4-methoxyacetophenone protects HT22 cells on glutamate induced cell-death in a dose-dependent manner (EC50=10.94 μM). 2,3-Dihydroxy-4-methoxyacetophenone inhibits [Ca2+] accumulation in HT22 cells and has antioxidantive activity[1].
In Vivo	2,3-dihydroxy-4-methoxyacetophenone (50mg/kg; po) improves the impairment of spatial memory induced by scopolamine[1].
References	[1]. Jin Bae Weon, et al. The Ameliorating Effects of 2,3-dihydroxy-4-methoxyacetophenone on Scopolamine-Induced Memory Impairment in Mice and Its Neuroprotective Activity. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6732-6.

HS Code	2914509090

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%