DC Chemicals Limited
China
Product Name: STA-21
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Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: OCHROMYCINONE
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Purity: 98.0%
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Contact: Ms Wang

28882-53-3

28882-53-3 structure

28882-53-3 structure

Name: STA-21(Ochromycinone)
Chemical Name: Ochromycinone
CAS Number: 28882-53-3
Molecular Formula: C₁₉H₁₄O₄
Molecular Weight: 306.31
Catalog: Signaling Pathways JAK/STAT Signaling STAT
Create Date: 2017-10-29 17:23:22
Modify Date: 2024-01-13 16:04:23
(+)-Ochromycinone is a natural antibiotic that potently inhibits STAT3. (+)-Ochromycinone is used in the researches of cancers and psoriasis[1][2].

Name	Ochromycinone
Synonyms	(3S)-8-Hydroxy-3-methyl-3,4-dihydro-1,7,12(2H)-tetraphenetrione (3S)-8-hydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione Benz[a]anthracene-1,7,12(2H)-trione, 3,4-dihydro-8-hydroxy-3-methyl-, (3S)- (3S)-8-hydroxy-3-methyl-3,4-dihydro-2H-benzo[a]anthracene-1,7,12-trione

Description	(+)-Ochromycinone is a natural antibiotic that potently inhibits STAT3. (+)-Ochromycinone is used in the researches of cancers and psoriasis[1][2].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> STAT Research Areas >> Inflammation/Immunology
References	[1]. Song H, et al. A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells. Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4700-5. [2]. Miyoshi K, et al. Stat3 as a therapeutic target for the treatment of psoriasis: a clinical feasibility study with STA-21, a Stat3 inhibitor. J Invest Dermatol. 2011 Jan;131(1):108-17.

Density	1.4±0.1 g/cm3
Boiling Point	568.6±50.0 °C at 760 mmHg
Melting Point	160-162ºC
Molecular Formula	C₁₉H₁₄O₄
Molecular Weight	306.31
Flash Point	311.7±26.6 °C
Exact Mass	306.089203
PSA	71.44000
LogP	4.86
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.667

HS Code	2914400090

Precursor 5
130548-10-6 127414-87-3 681001-30-9 1577-22-6
481-39-0
DownStream 0

HS Code	2914400090
Summary	2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%