34218-84-3
34218-84-3 structure
- Name: 2'-O-Methyl-5-Iodo-Uridine
- Chemical Name: 2'-(o-methyl)-5-iodouridine
- CAS Number: 34218-84-3
- Molecular Formula: C10H13IN2O6
- Molecular Weight: 384.12
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2018-07-16 08:05:12
- Modify Date: 2024-01-11 18:27:28
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2’-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 2'-(o-methyl)-5-iodouridine |
|---|---|
| Synonyms |
2'-OMe-5-I-Uridine
5-Iodo-2'-O-methyluridin 5-IODO-2'-O-METHYLURIDINE 2'-OMe-5-I-U Uridine,5-iodo-2'-O-Methyl 2'-O-Methyl-5-Iodo-Uridine |
| Description | 2’-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 2.04±0.1 g/cm3(Predicted) |
|---|---|
| Molecular Formula | C10H13IN2O6 |
| Molecular Weight | 384.12 |
| Exact Mass | 383.98200 |
| PSA | 113.78000 |
| Storage condition | 2-8℃ |
|
~72%
34218-84-3 |
| Literature: Kittaka, Atsushi; Kuze, Tetsuya; Asakura, Takashi; Ito, Katsutoshi; Miyasaka, Tadashi; Inoue, Jun-Ichiro Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 22 p. 3207 - 3210 |
| Precursor 1 | |
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| DownStream 0 | |