23986-74-5

23986-74-5 structure
23986-74-5 structure
  • Name: Germacrene D
  • Chemical Name: (1E,6E,8S)-1-methyl-5-methylene-8-(1-methylethyl)-1,6-cyclodecadiene
  • CAS Number: 23986-74-5
  • Molecular Formula: C15H24
  • Molecular Weight: 204.35100
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2017-03-24 10:49:54
  • Modify Date: 2024-01-02 19:40:22
  • Germacrene D is isolated from Bursera species. Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles[1].

Name (1E,6E,8S)-1-methyl-5-methylene-8-(1-methylethyl)-1,6-cyclodecadiene
Synonyms (-)-(7S)-germacrene D
(8S,1E,6E)-1-methyl-5-methylene-8-(1-methylethyl)-1,6-cyclodecadiene
(S)-germacrene D
(+)-germacrene-D
Description Germacrene D is isolated from Bursera species. Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles[1].
Related Catalog
Target

IC50: bacterial[1]

In Vitro Germacrene D shows antibacterial and antifungal activities, the mechanism of antimicrobial action of it may be related to permeabilization of the cells and disruption of the membrane integrity[1].
References

[1]. Noge K, et al. Germacrene D, a common sesquiterpene in the genus Bursera (Burseraceae).Molecules. 2009 Dec 15;14(12):5289-97.

Molecular Formula C15H24
Molecular Weight 204.35100
Exact Mass 204.18800
LogP 4.89130
Vapour Pressure 0.00673mmHg at 25°C
HS Code 2902199090
HS Code 2902199090
Summary 2902199090 other cyclanes, cyclenes and cyclotherpenes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%