953428-73-4
953428-73-4 structure
- Name: JNJ-39393406
- Chemical Name: 3-[3-[(2,2-difluoro-1,3-benzodioxol-5-yl)amino]-5-pyridin-4-yl-1,2,4-triazol-1-yl]-N,N-dimethylpropanamide
- CAS Number: 953428-73-4
- Molecular Formula: C19H18F2N6O3
- Molecular Weight: 416.38100
- Create Date: 2016-12-02 09:39:59
- Modify Date: 2025-08-25 19:16:11
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JNJ-39393406 is a potent, selective positive allosteric α7 nAChR modulator, potentiates a 100 μM choline-induced rise in intracellular calcium mediated by human α7 channels expressed in GH4C1 cells with EC50 of 660 nM.
| Name | 3-[3-[(2,2-difluoro-1,3-benzodioxol-5-yl)amino]-5-pyridin-4-yl-1,2,4-triazol-1-yl]-N,N-dimethylpropanamide |
|---|---|
| Synonyms | unii-t930sou82p |
| Molecular Formula | C19H18F2N6O3 |
|---|---|
| Molecular Weight | 416.38100 |
| Exact Mass | 416.14100 |
| PSA | 97.63000 |
| LogP | 2.30540 |