197855-65-5

197855-65-5 structure

Name: Z-FA-FMK
Chemical Name: z-phe-dl-ala-fluoromethylketone
CAS Number: 197855-65-5
Molecular Formula: C₂₁H₂₃FN₂O₄
Molecular Weight: 386.417
Catalog: Biochemical Inhibitor Proteases Cysteine Protease Inhibitor
Create Date: 2017-08-18 15:45:49
Modify Date: 2024-01-09 15:40:42
Z-FA-FMK ((1S)-Z-FA-FMK; Compound 6) is a broad-spectrum halomethyl ketone inhibitor sgainst Coronavirus (SARS-CoV) main protease 3CL with a Ki of 25.7 μM[1].

Name	z-phe-dl-ala-fluoromethylketone
Synonyms	z-fa-fmk UNII:34O3P3306Z Nα-[(Benzyloxy)carbonyl]-N-(4-fluoro-3-oxo-2-butanyl)phenylalaninamide Carbamic acid, N-[(1S)-2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-, phenylmethyl ester Carbamic acid, N-[2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-, phenylmethyl ester Nα-[(Benzyloxy)carbonyl]-N-(4-fluoro-3-oxo-2-butanyl)-L-phenylalaninamide

Description	Z-FA-FMK ((1S)-Z-FA-FMK; Compound 6) is a broad-spectrum halomethyl ketone inhibitor sgainst Coronavirus (SARS-CoV) main protease 3CL with a Ki of 25.7 μM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	Ki: 25.7 μM (SARS Protease 3CLpro)[1]
References	[1]. Usman Bacha, et al. Development of broad-spectrum halomethyl ketone inhibitors against coronavirus main protease 3CL(pro). Chem Biol Drug Des. 2008 Jul;72(1):34-49.