57773-63-4
57773-63-4 structure
- Name: [D-Trp6]-LH-RH
- Chemical Name: triptorelin
- CAS Number: 57773-63-4
- Molecular Formula: C64H82N18O13
- Molecular Weight: 1311.449
- Catalog: API Hormone and endocrine-regulating drugs Gonadotropin
- Create Date: 2018-03-20 08:00:00
- Modify Date: 2025-08-19 21:11:04
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Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferationIn vivo: (1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins.
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| Name | triptorelin |
|---|---|
| Synonyms |
5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycinamide
triptorelinum triptorelinum [INN_la] Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolyl- triptoreline TRIPORELIN MFCD00167541 triptorelina TRIPTORELIN AMIDE UNII:9081Y98W2V Triptorelin TRIPTORELIN PAMOATE Decapeptyl |
| Description | Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferationIn vivo: (1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C64H82N18O13 |
| Molecular Weight | 1311.449 |
| Exact Mass | 1310.630859 |
| PSA | 487.92000 |
| LogP | -0.41 |
| Index of Refraction | 1.723 |
| Storage condition | −20°C |
| Symbol |
GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H360 |
| Precautionary Statements | P201-P308 + P313 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T: Toxic; |
| Risk Phrases | R60 |
| Safety Phrases | 53-22-36/37/39-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |