828934-41-4

828934-41-4 structure

Name: Etomoxir (Na salt)
Chemical Name: sodium,(2R)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate
CAS Number: 828934-41-4
Molecular Formula: C₁₅H₁₈ClNaO₄
Molecular Weight: 320.744
Catalog: Research Areas Metabolic Disease
Create Date: 2018-12-24 18:32:30
Modify Date: 2024-01-10 16:00:07
(R)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt, acts as an inhibitorof carnitine palmitoyltransferase I (CPT-I), and inhibits palmitate β-oxidation in human, rat and guinea pig.

Name	sodium,(2R)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate
Synonyms	Sodium (2R)-2-[6-(4-chlorophenoxy)hexyl]-2-oxiranecarboxylate 2-Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, sodium salt, (2R)- (1:1) cc-140 (+)-Etomoxir (sodium salt) ANTI-EAPII(TTRAP) (2R)-2-[6-(4-Chlorophenoxy)hexyl]oxiranecarboxylic acid sodium salt MFCD07787411 (+)-Etomoxir sodium salt (R)-(+)-Etomoxir (sodium salt)

Description	(R)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt, acts as an inhibitorof carnitine palmitoyltransferase I (CPT-I), and inhibits palmitate β-oxidation in human, rat and guinea pig.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	CPT-1[1]
In Vitro	(R)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt, acts as an inhibitorof carnitine palmitoyltransferase I (CPT-I), and inhibits palmitate β-oxidation in human, rat and guinea pig[1].
References	[1]. Agius L, et al. Differences between human, rat and guinea pig hepatocyte cultures. A comparative study of their rates of beta-oxidation and esterification of palmitate and their sensitivity to R-etomoxir. Biochem Pharmacol. 1991 Oct 9;42(9):1711-5.