DC Chemicals Limited
China
Product Name: Debrisoquine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Debrisoquine
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ISOCARAMIDINE SULFATE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

581-88-4

581-88-4 structure

Name: DEBRISOQUIN SULFATE
Chemical Name: debrisoquin sulfate
CAS Number: 581-88-4
Molecular Formula: C₁₀H₁₃N_3.1/₂H₂O₄S
Molecular Weight: 224.27
Catalog: Chemical reagent Organic reagent Barium salt
Create Date: 2018-07-24 22:02:56
Modify Date: 2025-09-11 10:30:26
Debrisoquin (Isocaramidine) hemisulfate is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner, with an IC50 of 22μM. Debrisoquin hemisulfate can be used for antiviral research[1].

Name	debrisoquin sulfate
Synonyms	2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate (2:1) Debrisoquin hemisulfate Bis[3,4-dihydroisoquinolin-2(1H)-yl(imino)methanaminium] sulfate debrisoquine sulfate 3,4-Dihydroisoquinoline-2(1H)-carboximidamide sulfate (2:1) 3,4-Dihydro-2(1H)-isoquinolinecarboximidamide sulfate (2:1) Debrisoquin sulfate debrisoquine sulphate

Description	Debrisoquin (Isocaramidine) hemisulfate is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner, with an IC50 of 22μM. Debrisoquin hemisulfate can be used for antiviral research[1].
Related Catalog	Research Areas >> Infection
Target	Human Endogenous Metabolite

Boiling Point	309.8ºC at 760 mmHg
Melting Point	278-280°, 284-285° or 266-268° (H2O)
Molecular Formula	C₁₀H₁₃N_3.1/₂H₂O₄S
Molecular Weight	224.27
Flash Point	141.1ºC
Exact Mass	448.189270
PSA	189.20000
LogP	3.78020
Storage condition	-20°C Freezer
Water Solubility	H2O: 20 mg/mL with heat

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NW7010000

CAS REGISTRY NUMBER :: 581-88-4

LAST UPDATED :: 198804

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C10-H13-N3.1/2H2-O4-S

MOLECULAR WEIGHT :: 224.30

WISWESSER LINE NOTATION :: T66 CNT&J CYZUM & 2WSQQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 610 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 17,129,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 235 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 6,299,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 132 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 6,299,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 136 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 6,299,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 31700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 6,299,1964

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn
Risk Phrases	22
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	NW7010000
HS Code	2933499090

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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