112241-19-7
112241-19-7 structure
- Name: SMPT
- Chemical Name: (2,5-dioxopyrrolidin-1-yl) 4-[1-(pyridin-2-yldisulfanyl)ethyl]benzoate
- CAS Number: 112241-19-7
- Molecular Formula: C18H16N2O4S2
- Molecular Weight: 388.46100
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2017-05-26 23:40:55
- Modify Date: 2025-08-25 19:46:58
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SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
| Name | (2,5-dioxopyrrolidin-1-yl) 4-[1-(pyridin-2-yldisulfanyl)ethyl]benzoate |
|---|---|
| Synonyms |
1-({4-[1-(pyridin-2-yldisulfanyl)ethyl]benzoyl}oxy)pyrrolidine-2,5-dione
SMPT 2,5-Pyrrolidinedione,1-((4-(1-(2-pyridinyldithio)ethyl)benzoyl)oxy) |
| Description | SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
| References |
| Density | 1.43g/cm3 |
|---|---|
| Boiling Point | 547ºC at 760mmHg |
| Molecular Formula | C18H16N2O4S2 |
| Molecular Weight | 388.46100 |
| Flash Point | 284.6ºC |
| Exact Mass | 388.05500 |
| PSA | 127.17000 |
| LogP | 3.74180 |
| Vapour Pressure | 5.11E-12mmHg at 25°C |
| Index of Refraction | 1.675 |