Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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41544-24-5

41544-24-5 structure

Name: Tromantadine hydrochloride
Chemical Name: N-(1-adamantyl)-2-[2-(dimethylamino)ethoxy]acetamide,hydrochloride
CAS Number: 41544-24-5
Molecular Formula: C₁₆H₂₉ClN₂O₂
Molecular Weight: 316.86700
Catalog: Signaling Pathways Anti-infection HSV
Create Date: 2016-11-17 09:06:42
Modify Date: 2024-01-05 10:02:41
Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication[1].

Name	N-(1-adamantyl)-2-[2-(dimethylamino)ethoxy]acetamide,hydrochloride
Synonyms	Tromantadin hydrochlorid Viruserol UNII-H09LUS437B Virumerz Tromantadine HCl

Description	Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection
Target	HSV-1 HSV-2
In Vitro	Treatment of the cells with 10 to 50μg of Tromantadine reduces HSV-induced cytopathic effect. Treatment with 100 to 500μg of Tromantadine inhibits herpes simplex virus-induced cytopathic effect and reduces virus production. Complete inhibition of virus production is observed with treatments of 500μg to 1 mg. The antiherpetic activity of Tromantadine is dependent upon the viral inoculum size and the time of addition of the compound with respect to infection[1].
References	[1]. Rosenthal KS, et al. Tromantadine: inhibitor of early and late events in herpes simplex virus replication. Antimicrob Agents Chemother. 1982 Dec;22(6):1031-6.