4678-44-8
4678-44-8 structure
- Name: Grayanotoxin II
- Chemical Name: (3β,6β,14R)-Grayanotox-10-ene-3,5,6,14,16-pentol
- CAS Number: 4678-44-8
- Molecular Formula: C20H32O5
- Molecular Weight: 352.46500
- Catalog: Research Areas Neurological Disease
- Create Date: 2016-02-07 18:02:52
- Modify Date: 2024-02-04 20:39:43
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Grayanotoxin II is a potent analgesic agent, is a diterpenoid. Grayanotoxin II shows significant analgesic activity[1].
| Name | (3β,6β,14R)-Grayanotox-10-ene-3,5,6,14,16-pentol |
|---|---|
| Synonyms |
7-(prop-2-in-1-yloxy)-1-benzopyran-2-one
7-Propargyloxy-cumarin [German] 2H-1-Benzopyran-2-one,7-(2-propynyloxy) (7R)-1,1,8-Trimethyl-4-methylen-(3ac,4at)-dodecahydro-7r,9ac-methano-cyclopenta[b]heptalen-2t,8c,11t,11at,12anti-pentaol Grayanatoxin-II Grayanotoxin-II (3aR)-2c.8t.11c.11ac.12anti-Pentahydroxy-1.1.8c-trimethyl-4-methylen-(3arH.4acH)-tetradecahydro-7t.9at-methano-cyclopenta[b]heptalen Andromedenol (7-coumaryloxy)methylacetylene (7R)-1,1,8-trimethyl-4-methylene-(3ac,4at)-dodecahydro-7r,9ac-methano-cyclopenta[b]heptalene-2t,8c,11t,11at,12anti-pentaol (7-propargyloxy)coumarin 7-Propargyloxy-cumarin 7-(2-Propynyloxy)-2H-1-benzopyran-2-one 7-(prop-2-yn-1-yloxy)-2H-chromen-2-one |
| Description | Grayanotoxin II is a potent analgesic agent, is a diterpenoid. Grayanotoxin II shows significant analgesic activity[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Grayanotoxin II (5 mg/kg; i.p.) 在乙酸诱导的小鼠扭体试验中显示出显着的镇痛活性[1]。 Animal Model: Kunming mice (acetic acid-induced writhing test)[1] Dosage: 5 mg/kg Administration: I.p. Result: Showed significant analgesic activity in mice. |
| References |
| Density | 1.3g/cm3 |
|---|---|
| Boiling Point | 522.9ºC at 760 mmHg |
| Molecular Formula | C20H32O5 |
| Molecular Weight | 352.46500 |
| Flash Point | 237.9ºC |
| Exact Mass | 352.22500 |
| PSA | 101.15000 |
| LogP | 0.97350 |
| Index of Refraction | 1.61 |
| RIDADR | UN 3172 |
|---|---|
| Hazard Class | 6.1(a) |