404828-08-6

404828-08-6 structure

Name: GSK3 Inhibitor XIII
Chemical Name: N-(5-Methyl-1H-pyrazol-3-yl)-2-phenyl-4-quinazolinamine
CAS Number: 404828-08-6
Molecular Formula: C₁₈H₁₅N₅
Molecular Weight: 301.34500
Catalog: Signaling Pathways PI3K/Akt/mTOR GSK-3
Create Date: 2017-08-27 09:13:02
Modify Date: 2025-08-27 08:17:36
GSK-3 Inhibitor XIII is a potent and ATP-competitive GSK-3 inhibitor with a Ki of 24 nM[1][1][2].

Name	N-(5-Methyl-1H-pyrazol-3-yl)-2-phenyl-4-quinazolinamine
Synonyms	GSK3 Inhibitor XIII

Description	GSK-3 Inhibitor XIII is a potent and ATP-competitive GSK-3 inhibitor with a Ki of 24 nM[1][1][2].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> GSK-3 Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3
References	[1]. Albert C Pierce, et al. CH...O and CH...N hydrogen bonds in ligand design: a novel quinazolin-4-ylthiazol-2-ylamine protein kinase inhibitor. J Med Chem. 2005 Feb 24;48(4):1278-81. [2]. Eduardo Cruz Moraes, et al. Kinase inhibitor profile for human nek1, nek6, and nek7 and analysis of the structural basis for inhibitor specificity. Molecules. 2015 Jan 13;20(1):1176-91.