83701-16-0

83701-16-0 structure

Name: Lithocholic Acid-d4
Chemical Name: (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-2,2,4,4-tetradeuterio-3-hydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
CAS Number: 83701-16-0
Molecular Formula: C₂₄H₃₆D₄O₃
Molecular Weight: 380.59700
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-05-27 08:00:00
Modify Date: 2024-01-04 18:39:42
Lithocholic acid-d4 (3α-Hydroxy-5β-cholanic acid-d4) is the deuterium labeled Lithocholic acid, which is a toxic secondary bile acid[1].

Name	(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-2,2,4,4-tetradeuterio-3-hydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
Synonyms	3\|A-Hydroxy-5\|A-cholanic Acid-d4 Lithocholic acid-2,2,4,4-d4 3-Hydroxycholan-24-oic Acid-d4 Lithocholic Acid-d4 3\|A-Hydroxycholanic Acid-d4 <1,1,4,4-2H>-Lithocholsaeure 3\|A-Hydroxy-5\|A-cholanoic Acid-d4

Description	Lithocholic acid-d4 (3α-Hydroxy-5β-cholanic acid-d4) is the deuterium labeled Lithocholic acid, which is a toxic secondary bile acid[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Metabolic Disease
In Vitro	Lithocholic acid is a toxic secondary bile acid[1].
References	[1]. Staudinger JL, et al. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc Natl Acad Sci U S A. 2001;98(6):3369-3374.

Safety Phrases	22-24/25