Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: COLCHICINE, O(sup 1)-DEMETHYL-, ACETATE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

3306-60-3

3306-60-3 structure

Name: COLCHICINE, O(sup 1)-DEMETHYL-, ACETATE
Chemical Name: [(7S)-7-acetamido-2,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-1-yl] acetate
CAS Number: 3306-60-3
Molecular Formula: C₂₃H₂₅NO₇
Molecular Weight: 427.44700
Create Date: 2016-11-25 13:46:57
Modify Date: 2024-02-03 22:22:16

Name	[(7S)-7-acetamido-2,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-1-yl] acetate
Synonyms	1-O-acetyl-1-O-demethyl-colchicine 1-Demethyl-1-acetylcolchicine

Density	1.29g/cm3
Boiling Point	729.6ºC at 760 mmHg
Molecular Formula	C₂₃H₂₅NO₇
Molecular Weight	427.44700
Flash Point	395ºC
Exact Mass	427.16300
PSA	100.16000
LogP	3.17920
Index of Refraction	1.587

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GH0881000

CHEMICAL NAME :: Colchicine, O(sup 1)-demethyl-, acetate

CAS REGISTRY NUMBER :: 3306-60-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C23-H25-N-O7

MOLECULAR WEIGHT :: 427.49

WISWESSER LINE NOTATION :: L B677 MV&T&J COV1 DO1 EO1 JMV1 OO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 88 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,257,1981

64-86-8

75-36-5

~34%

3306-60-3

Literature: McDonald, Edward; Ramage, Robert; Woodhouse, Robert N.; Underbill, Edward W.; Wetter, Leslie R.; Battersby, Alan R. Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 18 p. 2979 - 2987

Precursor 2
64-86-8 75-36-5
DownStream 1
3464-68-4

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