2545-00-8

2545-00-8 structure

Name: (+)-Afzelechin
Chemical Name: afzelechin
CAS Number: 2545-00-8
Molecular Formula: C₁₅H₁₄O₅
Molecular Weight: 274.269
Catalog: Natural product Flavonoids
Create Date: 2017-12-10 07:37:37
Modify Date: 2025-08-25 12:48:50
(+)-Afzelechin, isolated from rhizomes of Bergenia ligulata, is an alpha-glucosidase activity inhibitor with an ID50 (50% inhibition dose) value of 0.13 mM. (+)-Afzelechin can delay the absorption of carbohydrates in food to suppress postprandial hyperglycemia and hyperinsulinemia[1].

Name	afzelechin
Synonyms	(2R,3R)-2-(4-Hydroxyphenyl)-3,5,7-chromanetriol (-)-epiafzelechin 2H-1-Benzopyran-3,5,7-triol, 3,4-dihydro-2-(4-hydroxyphenyl)-, (2R,3R)- Afzelechin 2H-1-Benzopyran-3,5,7-triol, 3,4-dihydro-2-(4-hydroxyphenyl)-, (2R,3S)- (2R,3R)-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol epi-Afzelechin 3,5,7,4'-Tetrahydroxyflavan (2R,3S)-2-(4-Hydroxyphenyl)-3,5,7-chromanetriol 2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol

Description	(+)-Afzelechin, isolated from rhizomes of Bergenia ligulata, is an alpha-glucosidase activity inhibitor with an ID50 (50% inhibition dose) value of 0.13 mM. (+)-Afzelechin can delay the absorption of carbohydrates in food to suppress postprandial hyperglycemia and hyperinsulinemia[1].
Related Catalog	Research Areas >> Metabolic Disease
Target	ID50: 0.13 mM (alpha-glucosidase)[1]
References	[1]. Junichi Saijyo, et al. Alpha-glucosidase Inhibitor From Bergenia Ligulata. J Oleo Sci. 2008;57(8):431-5.

Hazard Codes	Xi