Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4,4'-Dimethoxybenzil
Price: Check
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 4,4'-Dimethoxybenzil
Price: ￥118.0/5g ￥338.0/25g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

1226-42-2

1226-42-2 structure

1226-42-2 structure

Name: 4,4'-Dimethoxybenzil
Chemical Name: 4,4'-Dimethoxybenzil
CAS Number: 1226-42-2
Molecular Formula: C₁₆H₁₄O₄
Molecular Weight: 270.28000
Catalog: Chemical reagent Organic reagent Aromatic ketone
Create Date: 2018-07-06 17:02:08
Modify Date: 2025-08-20 21:46:19
4,4'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor with Ki of 70 nM.

Name	4,4'-Dimethoxybenzil
Synonyms	4,4′-Dimethoxybenzil MFCD00008405 EINECS 214-960-5 4,4‘-Dimethoxybenzil 1,2-bis(4-methoxyphenyl)ethane-1,2-dione

Description	4,4'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor with Ki of 70 nM.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer
Target	Ki: 70 nM (hiCE)[1]
In Vitro	By reducing irinotecaninduced diarrhea, hiCE inhibitors (e.g., 4,4'-Dimethoxybenzil, Compound 8) can improve the anti-cancer efficacy of irinotecan. To find effective hiCE inhibitors, a new virtual screening protocol that combines pharmacophore models derived from the hiCE structure and its ligands has been proposed[1].
References	[1]. GuoDong Zhang, et al. Predicting hiCE inhibitors based upon pharmacophore models derived from the receptor and its ligands. Science China Chemistry

Density	1.183g/cm3
Boiling Point	442.2ºC at 760 mmHg
Melting Point	132-134ºC(lit.)
Molecular Formula	C₁₆H₁₄O₄
Molecular Weight	270.28000
Flash Point	197.5ºC
Exact Mass	270.08900
PSA	52.60000
LogP	2.76940
Vapour Pressure	5.13E-08mmHg at 25°C
Index of Refraction	1.566

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	22-24/25-36/37-26
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2914509090

Precursor 9
120-44-5 119-52-8 2510-75-0 123-11-5
79-37-8 100-66-3 100-07-2 2132-62-9
14271-83-1
DownStream 10
1054543-47-3 107659-46-1 100-09-4 77336-73-3
94-30-4 639-61-2 121-98-2 123-11-5
4464-76-0 105-13-5

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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