68244-58-6

68244-58-6 structure

Name: OMP SODIUM SALT
Chemical Name: Orotidine 5′-monophosphate trisodium salt
CAS Number: 68244-58-6
Molecular Formula: C₁₀H₁₀N₂Na₃O₁₁P
Molecular Weight: 434.13600
Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
Create Date: 2017-02-14 01:19:11
Modify Date: 2025-08-25 19:16:46
Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT)[1].

Name	Orotidine 5′-monophosphate trisodium salt
Synonyms	3-[3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-2,6-dioxopyrimidine-4-carboxylic acid,sodium

Description	Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT)[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Metabolic Disease
Target	Human Endogenous Metabolite
References	[1]. Subrahmanyeswara Rao NN, et al. QM/MM reveals the sequence of substrate binding during OPRT action. Comput Biol Chem. 2018 Jun;74:31-38.

RIDADR	NONH for all modes of transport