DC Chemicals Limited
China
Product Name: Cinacalcet metabolite M4
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Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-(3-TRIFLUOROMETHYL-PHENYL)-PROPYLAMINE
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Purity: 98.0%
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Contact: Ms Wang

104774-87-0

104774-87-0 structure

104774-87-0 structure

Name: Cinacalcet metabolite M4
Chemical Name: 3-[3-(trifluoromethyl)phenyl]propan-1-amine
CAS Number: 104774-87-0
Molecular Formula: C₁₀H₁₂F₃N
Molecular Weight: 203.204
Catalog: Research Areas Cardiovascular Disease
Create Date: 2017-08-29 08:43:56
Modify Date: 2024-01-11 01:38:56
Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2].

Name	3-[3-(trifluoromethyl)phenyl]propan-1-amine
Synonyms	3-[3-(Trifluoromethyl)phenyl]-1-propanamine Benzenepropanamine, 3-(trifluoromethyl)-

Description	Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease
References	[1]. Kumar GN, et al. Metabolism and disposition of calcimimetic agent cinacalcet HCl in humans and animalmodels. Drug Metab Dispos. 2004 Dec;32(12):1491-500. [2]. Bushinsky DA, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92.

Density	1.2±0.1 g/cm3
Boiling Point	222.2±40.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₂F₃N
Molecular Weight	203.204
Flash Point	92.6±12.0 °C
Exact Mass	203.092178
PSA	26.02000
LogP	2.40
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.468

Hazard Codes	Xi
HS Code	2921499090

535-53-5 structure

535-53-5

~66%

104774-87-0 structure

104774-87-0

Literature: Wang, Xin; Chen, Ying; Crockett, Richard; Briones, Jorge; Yan, Tony; Orihuela, Carlos; Zhi, Benxin; Ng, John Tetrahedron Letters, 2004 , vol. 45, # 45 p. 8355 - 8358

60689-14-7 structure

60689-14-7

~%

104774-87-0 structure

104774-87-0

Literature: Tetrahedron Letters, , vol. 45, # 45 p. 8355 - 8358

64380-24-1 structure

64380-24-1

~%

104774-87-0 structure

104774-87-0

Literature: Tetrahedron Letters, , vol. 45, # 45 p. 8355 - 8358

93040-58-5 structure

93040-58-5

~%

104774-87-0 structure

104774-87-0

Literature: Bioorganic and Medicinal Chemistry, , vol. 5, # 8 p. 1675 - 1683

779-89-5 structure

779-89-5

~%

104774-87-0 structure

104774-87-0

Literature: Bioorganic and Medicinal Chemistry, , vol. 5, # 8 p. 1675 - 1683

Precursor 5
535-53-5 60689-14-7 64380-24-1 93040-58-5
779-89-5
DownStream 0

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%