577-38-8

577-38-8 structure

Name: (S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one
Chemical Name: flavanomarein
CAS Number: 577-38-8
Molecular Formula: C₂₁H₂₂O₁₁
Molecular Weight: 450.39300
Catalog: Research Areas Cardiovascular Disease
Create Date: 2017-01-13 11:15:47
Modify Date: 2025-08-22 16:27:22
Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities[1][2].

Name	flavanomarein
Synonyms	isookanin-7-o-glucoside 7-o-glucosyl-4',5',8-trihydroxyflavanone isookanin-7-glucoside 3',4',7,8-tetrahydroxyflavanone-7-o-glucoside trihydroxyflavanone

Description	Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Nan-Nan Zhang, et al. Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase. Sci Rep. 2020 Jan 16;10(1):439. [2]. Liang Le, et al. The protective effects of the native flavanone flavanomarein on neuronal cells damaged by 6-OHDA. Phytomedicine. 2019 Feb;53:193-204.

Hazard Codes	Xi