950-99-2

950-99-2 structure

Name: 2H-1-Benzopyran-6-ol,3,4-dihydro-2,2,5,7,8-pentamethyl-
Chemical Name: 2,2,5,7,8-pentamethyl-3,4-dihydrochromen-6-ol
CAS Number: 950-99-2
Molecular Formula: C₁₄H₂₀O₂
Molecular Weight: 220.30700
Catalog: Research Areas Cancer
Create Date: 2018-12-20 17:05:53
Modify Date: 2025-09-15 04:49:06
2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines[1].

Name	2,2,5,7,8-pentamethyl-3,4-dihydrochromen-6-ol
Synonyms	PMHCR 2H-1-Benzopyran-6-ol,3,4-dihydro-2,2,5,7,8-pentamethyl 2,2,5,7,8-pentamethyl-6-hydroxy-chromane MFCD00210347 Chromane C1 6-Hydroxy-2,2,5,7,8-pentamethylchroman 2,2,5,7,8-pentamethylchroman-6-ol 2,2,5,7,8-Pentamethyl-1-hydroxychroman 2,2,5,7,8-Pentamethyl-6-hydroxychroman 2,2,5,7,8-Pentamethyl-6-chromanol Chroman C1

Description	2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Androgen Receptor
References	[1]. Kyriakopoulos CE, et al. A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer. Invest New Drugs. 2016 Apr;34(2):225-30.

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%