Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Methoxy-3,4-dihydro-2H-pyran
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 3,4-Dihydro-2-Methoxy-2H-Pyran
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

4454-05-1

4454-05-1 structure

Name: (2R)-2-Methoxy-3,4-dihydro-2H-pyran
Chemical Name: 3,4-Dihydro-2-Methoxy-2H-Pyran
CAS Number: 4454-05-1
Molecular Formula: C₆H₁₀O₂
Molecular Weight: 114.142
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyran compound
Create Date: 2018-12-28 17:57:38
Modify Date: 2025-08-19 21:46:37

Name	3,4-Dihydro-2-Methoxy-2H-Pyran
Synonyms	2-Methoxy-3,4-dihydro-2H-pyran 3,4-Dihydro-2-Methoxy-2H-pyran MFCD00006560 (2R)-2-Methoxy-3,4-dihydro-2H-pyran 2H-Pyran, 3,4-dihydro-2-methoxy-, (2R)- EINECS 224-698-3

Density	1.0±0.1 g/cm3
Boiling Point	149.3±39.0 °C at 760 mmHg
Molecular Formula	C₆H₁₀O₂
Molecular Weight	114.142
Flash Point	16.7±0.0 °C
Exact Mass	114.068077
PSA	18.46000
LogP	-0.09
Vapour Pressure	5.1±0.3 mmHg at 25°C
Index of Refraction	1.451
Storage condition	Flammables area

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UP7900000

CHEMICAL NAME :: 2H-Pyran, 3,4-dihydro-2-methoxy-

CAS REGISTRY NUMBER :: 4454-05-1

BEILSTEIN REFERENCE NO. :: 0107274

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C6-H10-O2

MOLECULAR WEIGHT :: 114.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1410 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - other changes

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8044 ppm/1H

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - pleural effusion

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 4920 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - dyspnea Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988

Hazard Codes	F:Highlyflammable;Xn:Harmful;
Risk Phrases	R11;R22
Safety Phrases	S9-S33-S16-S36-S26
RIDADR	1993
RTECS	UP7900000
Packaging Group	II
Hazard Class	3
HS Code	2932999099

107-25-5

107-02-8

~92%

4454-05-1

Literature: SHOWA DENKO K.K. Patent: WO2006/62211 A1, 2006 ; Location in patent: Page/Page column 25 ;

107-25-5

123-31-9

107-02-8

4454-05-1

Literature: Journal of the American Chemical Society, , vol. 72, p. 3079 Journal of the American Chemical Society, , vol. 73, p. 5251,5269

67-56-1

142-29-0

~0%

4454-05-1

6026-86-4

Detail

Literature: Chemische Berichte, , vol. 115, # 8 p. 2697 - 2706

Precursor 5
107-25-5 107-02-8 123-31-9 67-56-1
142-29-0
DownStream 10
220370-51-4 626-60-8 2457-47-8 6581-66-4
142-68-7 67-56-1 6581-57-3 6975-85-5
112698-08-5 16015-12-6

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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