Shanghai Nianxing Industrial Co., Ltd
China
Product Name: methacycline
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Purity: 90.0%
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914-00-1

914-00-1 structure

914-00-1 structure

Name: methacycline
Chemical Name: methacycline
CAS Number: 914-00-1
Molecular Formula: C₂₂H₂₂N₂O₈
Molecular Weight: 442.41900
Catalog: API Antibiotics Tetracycline
Create Date: 2018-02-15 08:00:00
Modify Date: 2025-08-24 18:58:12

Name	methacycline
Synonyms	Germicilclin Adriamicina gs-2876 6-methylene-oxytetracyclin METHACYCLINE Globociclina 6-methyleneoxytetracycline rondomycin metacycline bialatan methacyclineamphoteric Cyclobiotic 12aalpha))-ph

Density	1.66g/cm3
Boiling Point	695.1ºC at 760mmHg
Melting Point	>150°C (dec.) (lit.)
Molecular Formula	C₂₂H₂₂N₂O₈
Molecular Weight	442.41900
Flash Point	374.2ºC
Exact Mass	442.13800
PSA	181.62000
LogP	0.26240
Index of Refraction	1.753
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QI9275000

CHEMICAL NAME :: 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro- 3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-

CAS REGISTRY NUMBER :: 914-00-1

LAST UPDATED :: 199506

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C22-H22-N2-O8

MOLECULAR WEIGHT :: 442.46

WISWESSER LINE NOTATION :: L E6 C666 BV FV MY CU GU LHTT&&J DQ EQ GVZ HQ IN1&1 KQ MU1 RQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 660 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 3750 ug/L

REFERENCE :: BCPHBM British Journal of Clinical Pharmacology. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1974- Volume(issue)/page/year: 16,127,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1538 No. of Facilities: 11 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1150 (estimated) No. of Female Employees: 591 (estimated)

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