99697-24-2
99697-24-2 structure
- Name: 24-Norursodeoxycholic acid
- Chemical Name: 24-Norcholan-23-oic acid, 3,7-dihydroxy-, (3α,5β,7β)
- CAS Number: 99697-24-2
- Molecular Formula: C23H38O4
- Molecular Weight: 378.54500
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2016-08-15 18:30:09
- Modify Date: 2024-01-02 16:43:13
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24-norursodeoxycholic acid (norUDCA) is a side chain-shortened C23 homologue of UDCA and has shown potent anti-cholestatic, anti-inflammatory and anti-fibrotic properties.
| Name | 24-Norcholan-23-oic acid, 3,7-dihydroxy-, (3α,5β,7β) |
|---|---|
| Synonyms |
24-norursodeoxycholic acid
3α,7β-Dihydroxy-24-nor-5β-cholan-23-oic acid Norursodeoxycholic acid 24-Norursodeoxycholic acid 24-Nor Ursodeoxycholic Acid |
| Description | 24-norursodeoxycholic acid (norUDCA) is a side chain-shortened C23 homologue of UDCA and has shown potent anti-cholestatic, anti-inflammatory and anti-fibrotic properties. |
|---|---|
| Related Catalog | |
| In Vitro | 24-norursodeoxycholic acid (norUDCA) is a side chain-shortened C23 homologue of UDCA and is previously shown to be highly effective in preclinical mouse models of cholestatic and fibrotic liver diseases. 24-norursodeoxycholic acid significantly reduces serum alkaline phosphatase (ALP) levels in a dose-dependent fashion. 24-norursodeoxycholic acid also significantly reduces γ-GT, ALT, and AST serum levels[1]. |
| References |
| Density | 1.142±0.06 g/cm3 (20 °C, 760 mmHg) |
|---|---|
| Boiling Point | 536.7±25.0 °C (760 mmHg) |
| Molecular Formula | C23H38O4 |
| Molecular Weight | 378.54500 |
| Exact Mass | 378.27700 |
| PSA | 77.76000 |
| LogP | 4.08780 |
| Storage condition | 2-8℃ |