1189929-21-2

1189929-21-2 structure

Name: 5-O-Desmethyl donepezil-d5
Chemical Name: 5-hydroxy-6-methoxy-2-[[1-[(2,3,4,5,6-pentadeuteriophenyl)methyl]piperidin-4-yl]methyl]-2,3-dihydroinden-1-one
CAS Number: 1189929-21-2
Molecular Formula: C₂₃H₂₂D₅NO₃
Molecular Weight: 370.50
Create Date: 2016-04-30 16:14:09
Modify Date: 2025-11-18 17:03:07
5-O-Desmethyl donepezil-d5 is deuterium labeled 5-O-Desmethyl donepezil.

Name	5-hydroxy-6-methoxy-2-[[1-[(2,3,4,5,6-pentadeuteriophenyl)methyl]piperidin-4-yl]methyl]-2,3-dihydroinden-1-one
Synonyms	5-O-Desmethyl Donepezil-d5

Description	5-O-Desmethyl donepezil-d5 is deuterium labeled 5-O-Desmethyl donepezil.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.