- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: diosbulbin d
- Price: Check
- Purity: 95.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- BioBioPha
- China
- Product Name: diosbulbin d
- Price: ￥4650.0/5mg
- Purity: 96.0%
- Stocking Period: 10 Day
- Contact: Xueping-Zheng
- Email: 1477035482@qq.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: diosbulbin d
- Price: ￥5600.0/5mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Diosbulbin D
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
66756-57-8
66756-57-8 structure
- Name: diosbulbin d
- Chemical Name: 2-(furan-3-yl)-11b-methyloctahydro-2h-7,10-methanooxepino[4,5-f]isochromene-4,6,8(1h)-trione
- CAS Number: 66756-57-8
- Molecular Formula: C19H20O6
- Molecular Weight: 344.36
- Catalog: Natural product Moss
- Create Date: 2018-03-20 08:00:00
- Modify Date: 2025-08-27 11:05:47
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Diosbulbin D is a potential hepatotoxic compound that can be isolated from Dioscorea bulbifera L.. Diosbulbin D induces apoptosis in L-02 cells[1].
| Name | 2-(furan-3-yl)-11b-methyloctahydro-2h-7,10-methanooxepino[4,5-f]isochromene-4,6,8(1h)-trione |
|---|---|
| Synonyms |
(1S,2S,5S,8S,10R,11R,13S)-8-(3-Furyl)-10-methyl-7,14-dioxatetracyclo[11.2.1.0.0]hexadecane-3,6,15-trione
7,10-Methano-2H-pyrano[4,3-g][3]benzoxepin-4,6,8(1H)-trione, 2-(3-furanyl)octahydro-11b-methyl-, (2S,4aS,6aS,7S,10S,11aR,11bR)- 7,10-Methano-2H-pyrano[4,3-g][3]benzoxepin-4,6,8(1H)-trione, 2-(3-furanyl)octahydro-11b-methyl- 8-(3-Furyl)-10-methyl-7,14-dioxatetracyclo[11.2.1.0.0]hexadecane-3,6,15-trione diosbulbin-d |
| Description | Diosbulbin D is a potential hepatotoxic compound that can be isolated from Dioscorea bulbifera L.. Diosbulbin D induces apoptosis in L-02 cells[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Diosbulbin D (10-80 μM; 12-72 h) 可诱导人正常肝脏 L-02 细胞毒性[1]。 Diosbulbin D (40 μM; 24 h) 诱导 L-02 细胞形态改变[1]。 Diosbulbin D (20-80 μM; 12-48 h) 诱导 L-02 细胞凋亡，并呈时间和浓度依赖性[1]。 Diosbulbin D (20-80 μM; 24 h) 诱导 L-02 细胞 caspase 3 的激活[1]。 Cell Viability Assay[1] Cell Line: L-02 cells Concentration: 10, 20, 40 and 80 μM Incubation Time: 12, 24, 48 and 72 h Result: Decreased L-02 cells viability in a concentration- and time-dependent manner. Apoptosis Analysis[1] Cell Line: L-02 cells Concentration: 20, 40 and 80 μM Incubation Time: 12, 24 and 48 h Result: Induced apoptosis in a time- and concentration-dependent manner. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 599.1±50.0 °C at 760 mmHg |
| Molecular Formula | C19H20O6 |
| Molecular Weight | 344.36 |
| Flash Point | 316.2±30.1 °C |
| Exact Mass | 344.125977 |
| PSA | 82.81000 |
| LogP | -0.35 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.556 |
| Hazard Codes | Xi |
|---|