15959-53-2

15959-53-2 structure

Name: N-Phenylsulfamide
Chemical Name: (sulfamoylamino)benzene
CAS Number: 15959-53-2
Molecular Formula: C₆H₈N₂O₂S
Molecular Weight: 172.20500
Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
Create Date: 2016-04-13 15:56:34
Modify Date: 2024-01-09 08:23:46
Phenylsulfamide (Compound 10) is a human carbonic anhydrase-II (hCA-II) inhibitor with a Kd of 45.50 μM and a Ki of 79.60 μM[1].

Name	(sulfamoylamino)benzene
Synonyms	aniline sulfonic acid amide Phenyl-sulfamid 4-sulfamoylaminobenzene sulfamoylphenylamide phenylsulfamide Schwefelsaeure-amid-anilid N-phenyl sulfamide Sulfamide,phenyl

Description	Phenylsulfamide (Compound 10) is a human carbonic anhydrase-II (hCA-II) inhibitor with a Kd of 45.50 μM and a Ki of 79.60 μM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	hCA II:45.50 μM (Kd) hCA II:79.60 μM (Ki)
References	[1]. Klinger AL, et al. Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements. J Med Chem. 2006 Jun 15;49(12):3496-500.