414864-00-9
414864-00-9 structure
- Name: Belinostat (PXD101)
- Chemical Name: belinostat
- CAS Number: 414864-00-9
- Molecular Formula: C15H14N2O4S
- Molecular Weight: 318.348
- Catalog: Biochemical Inhibitor Epigenetics HDAC inhibitor
- Create Date: 2018-09-30 11:29:24
- Modify Date: 2024-01-02 08:32:02
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Belinostat (PXD101) is a novel pan-HDAC inhibitor with IC50 of 27 nM, with activity demonstrated in cisplatin-resistant tumors.
| Name | belinostat |
|---|---|
| Synonyms |
Beleodaq
2-Propenamide, N-hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-, (2E)- Belinostat N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PROPENAMIDE (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide PXD101 (2E)-N-Hydroxy-3-[3-(phenylsulfamoyl)phenyl]acrylamide (E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C15H14N2O4S |
| Molecular Weight | 318.348 |
| Exact Mass | 318.067413 |
| PSA | 103.88000 |
| LogP | 2.23 |
| Appearance | white solid |
| Index of Refraction | 1.667 |
| Storage condition | -20℃ |
| HS Code | 2935009090 |
|---|
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |