3902-71-4

3902-71-4 structure

Name: Trioxsalen
Chemical Name: trioxsalen
CAS Number: 3902-71-4
Molecular Formula: C₁₄H₁₂O₃
Molecular Weight: 228.243
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyran compound
Create Date: 2018-02-25 08:00:00
Modify Date: 2024-01-08 22:50:35
Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.

Name	trioxsalen
Synonyms	EINECS 223-459-0 4,2',8-trimethylpsoralen 4,5',8-Trimethylpsoralen 2,5,9-Trimethyl-7H-furo[3,2-g]chromen-7-one Trisoralen 7H-Furo(3,2-g)(1)benzopyran-7-one, 2,5,9-trimethyl- 6-Hydroxy-β,2,7-trimethyl-5-benzofuranacrylic Acid δ-Lactone 2,5,9-Trimethyl-7H-furo[3,2-g][1]benzopyran-7-one 2,5,9-trimethylfuro[3,2-g]chromen-7-one Trioxysalenum Trioxysalene UNII-Y6UY8OV51T Trioxisaleno 7H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl- trioxysalen MFCD00005010 Elder 8011 4,5′,8-Trimethylpsoralen Trioxsalen 4,5‘,8-Trimethylpsoralen 2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one Trimethylpsoralen

Description	Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BICHAW Biochemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1962- Volume(issue)/page/year: 20,1431,1981 *** REVIEWS *** IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,357,1986 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,357,1986 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,366,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5360 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 340 (estimated) No. of Female Employees: 180 (estimated)

Symbol	GHS05, GHS08
Signal Word	Danger
Hazard Statements	H314-H351
Precautionary Statements	P260-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	C: Corrosive;
Risk Phrases	R34;R40
Safety Phrases	26-36/37/39-45
RIDADR	UN 1759 8
WGK Germany	2
RTECS	LV1576000
HS Code	2932999099

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

3902-71-4	78407-21-3
86996-93-2	84067-18-5