59587-09-6

59587-09-6 structure

Name: N-Acetyl-L-cysteine ethyl ester
Chemical Name: ethyl (2R)-2-acetamido-3-sulfanylpropanoate
CAS Number: 59587-09-6
Molecular Formula: C₇H₁₃NO₃S
Molecular Weight: 191.25
Catalog: Research Areas Metabolic Disease
Create Date: 2018-04-21 08:00:00
Modify Date: 2025-08-26 10:57:27
N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant[1].

Name	ethyl (2R)-2-acetamido-3-sulfanylpropanoate
Synonyms	L-2-Acetamino-3-mercapto-propionsaeure-aethylester N-Acetylcysteine ethylester N-acetyl-L-cysteine ethyl ester L-Cysteine,N-acetyl-,ethyl ester N-Acetyl-L-cystein-aethylester

Description	N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant[1].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	N-Acetyl-L-cysteine ethyl ester is a an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant[1].
References	[1]. Daniela Giustarini, et al. N-Acetylcysteine ethyl ester (NACET): a novel lipophilic cell-permeable cysteine derivative with an unusual pharmacokinetic feature and remarkable antioxidant potential. Biochem Pharmacol. 2012 Dec 1;84(11):1522-33.

Hazard Codes	Xi

84310-90-7

~44%

59587-09-6

Literature: Kemp, D. S.; Leung, See-Lap; Kerkman, Daniel J. Tetrahedron Letters, 1981 , vol. 22, p. 181 - 184

64-17-5

616-91-1

~47%

59587-09-6

Literature: Uhrig, Rainer K.; Picard, Martin A.; Beyreuther, Konrad; Wiessler, Manfred Carbohydrate Research, 2000 , vol. 325, # 1 p. 72 - 80

118143-52-5

59587-09-6

Literature: Kemp, D. S.; Leung, See-Lap; Kerkman, Daniel J. Tetrahedron Letters, 1981 , vol. 22, p. 181 - 184

24037-21-6

59587-09-6

Literature: Lucas; King Biochemical Journal, <1932>2084

Precursor 4
84310-90-7 64-17-5 616-91-1 118143-52-5
DownStream 0