Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 8-BENZYL-1-OXA-3,8-DIAZASPIRO[4.5]DECAN-2-ONE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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5053-14-5

5053-14-5 structure

Name: 8-Benzyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Chemical Name: 8-Benzyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS Number: 5053-14-5
Molecular Formula: C₁₄H₁₈N₂O₂
Molecular Weight: 246.30500
Create Date: 2018-12-04 12:28:20
Modify Date: 2024-01-07 21:26:01

Name	8-Benzyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Synonyms	8-benzyl-1-oxa-2-oxo-3,8-diazospiro<4,5>decane 8-benzyl-1-oxa-3,8-diazaspiro<4.5>decan-2-one

Density	1.22g/cm3
Boiling Point	457.1ºC at 760 mmHg
Molecular Formula	C₁₄H₁₈N₂O₂
Molecular Weight	246.30500
Flash Point	230.2ºC
Exact Mass	246.13700
PSA	45.06000
LogP	1.33890
Index of Refraction	1.6

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RO0220000

CHEMICAL NAME :: 1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-benzyl-

CAS REGISTRY NUMBER :: 5053-14-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H18-N2-O2

MOLECULAR WEIGHT :: 246.34

WISWESSER LINE NOTATION :: T6N CXTJ A1R& C-& DT5MVOX EHJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 319 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 4,185,1969

HS Code	2934999090

23804-68-4

5053-14-5

Literature: Merck and Co., Inc. Patent: US6172076 B2, 2001 ; US 6172076 B1

77211-73-5

5053-14-5

Literature: Caroon; Clark; Kluge; Nelson; Strosberg; Unger; Michel; Whiting Journal of Medicinal Chemistry, 1981 , vol. 24, # 11 p. 1320 - 1328

32315-10-9

23804-68-4

~74%

5053-14-5

Literature: Somanathan; Rivero; Nunez; Hellberg Synthetic Communications, 1994 , vol. 24, # 10 p. 1483 - 1487

6094-60-6

5053-14-5

Literature: Methot, Joey L.; Hoffman, Dawn Mampreian; Witter, David J.; Stanton, Matthew G.; Harrington, Paul; Hamblett, Christopher; Siliphaivanh, Phieng; Wilson, Kevin; Hubbs, Jed; Heidebrecht, Richard; Kral, Astrid M.; Ozerova, Nicole; Fleming, Judith C.; Wang, Hongmei; Szewczak, Alexander A.; Middleton, Richard E.; Hughes, Bethany; Cruz, Jonathan C.; Haines, Brian B.; Chenard, Melissa; Kenific, Candia M.; Harsch, Andreas; Secrist, J. Paul; Miller, Thomas A. ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 4 p. 340 - 345

3612-20-2

5053-14-5

Literature: Somanathan; Rivero; Nunez; Hellberg Synthetic Communications, 1994 , vol. 24, # 10 p. 1483 - 1487

156215-49-5

5053-14-5

Literature: Somanathan; Rivero; Nunez; Hellberg Synthetic Communications, 1994 , vol. 24, # 10 p. 1483 - 1487

23804-68-4

105-58-8

5053-14-5

Literature: Regnier,G. et al. Chimica Therapeutica, 1969 , vol. 4, p. 185 - 194

23804-68-4

530-62-1

5053-14-5

Precursor 7
23804-68-4 77211-73-5 32315-10-9 6094-60-6
3612-20-2 105-58-8 530-62-1
DownStream 6
23804-85-5 23804-80-0 77225-15-1 5052-95-9
5053-04-3 5229-89-0

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5053-14-5	23804-95-7
77211-46-2	6094-61-7
5053-07-6	1031928-36-5
5052-99-3	23804-80-0
5053-04-3	6110-67-4