123548-56-1

123548-56-1 structure

Name: 3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile
Chemical Name: [2-[3-[(2-acetyloxyacetyl)amino]-2-chloro-5-cyanoanilino]-2-oxoethyl] acetate
CAS Number: 123548-56-1
Molecular Formula: C₁₅H₁₄ClN₃O₆
Molecular Weight: 367.74100
Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
Create Date: 2016-01-31 16:06:27
Modify Date: 2025-08-26 09:18:53
Acreozast (TYB-2285) is a histamine release inhibitor. Acreozast inhibits the histamine release primed with IL-3. Acreozast might regulate allergic inflammation in vivo by the suppression of mediator release primed with IL-3[1].

Name	[2-[3-[(2-acetyloxyacetyl)amino]-2-chloro-5-cyanoanilino]-2-oxoethyl] acetate
Synonyms	Acreozast Acreozst Tyb-2285 UNII-84DZ9RW4WK

Description	Acreozast (TYB-2285) is a histamine release inhibitor. Acreozast inhibits the histamine release primed with IL-3. Acreozast might regulate allergic inflammation in vivo by the suppression of mediator release primed with IL-3[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
References	[1]. Watanabe A, et al. Effect of TYB-2285 on antigen-induced histamine release from mouse bone marrow-derived persisting cells (P-cells) primed with interleukin-3-containing conditioned medium (IL3-CM). Gen Pharmacol. 1993 Sep;24(5):1207-11.

34207-46-0

13831-31-7

~29%

123548-56-1

Precursor 2
34207-46-0 13831-31-7
DownStream 0