| 
                                    
                                    CHEMICAL IDENTIFICATION
 
  RTECS NUMBER :
 
  NK9460700
  
 
  CAS REGISTRY NUMBER :
 
  569-59-5
  
 
  LAST UPDATED :
 
  199709
  
 
  DATA ITEMS CITED :
 
  9
  
 
  MOLECULAR FORMULA :
 
  C19-H19-N.C4-H6-O6
  
 
  MOLECULAR WEIGHT :
 
  411.49
  
 
  WISWESSER LINE NOTATION :
 
  T B656 EN HHT&&J E1 HR &OVYQYQVO
  HEALTH HAZARD DATAACUTE TOXICITY DATA
 
  TYPE OF TEST :
 
  LD50 - Lethal dose, 50 percent kill
  
 
  ROUTE OF EXPOSURE :
 
  Oral
  
 
  SPECIES OBSERVED :
 
  Rodent - rat
  
 
  DOSE/DURATION :
 
  280 mg/kg
  
 
  TOXIC EFFECTS :
 
  Details of toxic effects not reported other than lethal dose value
  
 
  REFERENCE :
 
  29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,91,1969
  
 
  TYPE OF TEST :
 
  LDLo - Lowest published lethal dose
  
 
  ROUTE OF EXPOSURE :
 
  Subcutaneous
  
 
  SPECIES OBSERVED :
 
  Rodent - rat
  
 
  DOSE/DURATION :
 
  200 mg/kg
  
 
  TOXIC EFFECTS :
 
  Behavioral - tremor Behavioral - excitement
  
 
  REFERENCE :
 
  CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 144,887,1950
  
 
  TYPE OF TEST :
 
  LD50 - Lethal dose, 50 percent kill
  
 
  ROUTE OF EXPOSURE :
 
  Oral
  
 
  SPECIES OBSERVED :
 
  Rodent - mouse
  
 
  DOSE/DURATION :
 
  265 mg/kg
  
 
  TOXIC EFFECTS :
 
  Details of toxic effects not reported other than lethal dose value
  
 
  REFERENCE :
 
  JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 105,291,1952
  
 
  TYPE OF TEST :
 
  LD50 - Lethal dose, 50 percent kill
  
 
  ROUTE OF EXPOSURE :
 
  Intraperitoneal
  
 
  SPECIES OBSERVED :
 
  Rodent - mouse
  
 
  DOSE/DURATION :
 
  88 mg/kg
  
 
  TOXIC EFFECTS :
 
  Cardiac - other changes
  
 
  REFERENCE :
 
  JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 105,291,1952
  
 
  TYPE OF TEST :
 
  LD50 - Lethal dose, 50 percent kill
  
 
  ROUTE OF EXPOSURE :
 
  Intravenous
  
 
  SPECIES OBSERVED :
 
  Rodent - mouse
  
 
  DOSE/DURATION :
 
  18 mg/kg
  
 
  TOXIC EFFECTS :
 
  Details of toxic effects not reported other than lethal dose value
  
 
  REFERENCE :
 
  CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03034
  
 
  TYPE OF TEST :
 
  LD50 - Lethal dose, 50 percent kill
  
 
  ROUTE OF EXPOSURE :
 
  Oral
  
 
  SPECIES OBSERVED :
 
  Rodent - rabbit
  
 
  DOSE/DURATION :
 
  577 mg/kg
  
 
  TOXIC EFFECTS :
 
  Details of toxic effects not reported other than lethal dose value
  
 
  REFERENCE :
 
  29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,91,1969
  
 
  TYPE OF TEST :
 
  LD50 - Lethal dose, 50 percent kill
  
 
  ROUTE OF EXPOSURE :
 
  Intravenous
  
 
  SPECIES OBSERVED :
 
  Rodent - guinea pig
  
 
  DOSE/DURATION :
 
  24500 ug/kg
  
 
  TOXIC EFFECTS :
 
  Details of toxic effects not reported other than lethal dose value
  
 
  REFERENCE :
 
  AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 113,313,1958 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83541 No. of Facilities: 88 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 2790 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83541 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 82 (estimated) No. of Female Employees: 14 (estimated)
  |