CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UT7610000
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CHEMICAL NAME :
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1(4H)-Pyridinepropionic acid, alpha-amino-3-hydroxy-4-oxo-
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CAS REGISTRY NUMBER :
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10182-82-8
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LAST UPDATED :
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198910
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DATA ITEMS CITED :
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6
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MOLECULAR FORMULA :
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C8-H10-N2-O4
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MOLECULAR WEIGHT :
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198.20
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WISWESSER LINE NOTATION :
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T6N DVJ A1YZVQ CQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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6318 mg/kg
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SEX/DURATION :
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female 1-19 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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5558 mg/kg
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SEX/DURATION :
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female 1-19 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Maternal Effects - uterus, cervix, vagina
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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22750 mg/kg
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SEX/DURATION :
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female 42 day(s) pre-mating
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TOXIC EFFECTS :
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Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
MUTATION DATA
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TYPE OF TEST :
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Mutation test systems - not otherwise specified
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TEST SYSTEM :
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Human Cells - not otherwise specified
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DOSE/DURATION :
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200 umol/L
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REFERENCE :
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TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 9,241,1971 *** REVIEWS *** TOXICOLOGY REVIEW 32XPAD "Teratology," Berry, C.L., and D.E. Poswillo, eds., New York, Springer, 1975 Volume(issue)/page/year: -,49,1975
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