84845-75-0
84845-75-0 structure
- Name: Niperotidine
- Chemical Name: N-(1,3-benzodioxol-5-ylmethyl)-N'-[2-[[5-[(dimethylamino)methyl]furfuryl]thio]ethyl]-2-nitrovinylidenediamine
- CAS Number: 84845-75-0
- Molecular Formula: C20H26N4O5S
- Molecular Weight: 434.50900
- Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
- Create Date: 2018-09-21 11:29:50
- Modify Date: 2024-01-12 09:30:23
-
Niperotidine is a histamine H2-receptor antagonist.
| Name | N-(1,3-benzodioxol-5-ylmethyl)-N'-[2-[[5-[(dimethylamino)methyl]furfuryl]thio]ethyl]-2-nitrovinylidenediamine |
|---|---|
| Synonyms |
Niperotidine
Piperotidine N-(1,3-Benzodioxol-5-ylmethyl)-N'-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitro-1,1-ethenediamine Piperonylranitidine PiperotidineHCl Piperonylranitidinehydrochloride |
| Description | Niperotidine is a histamine H2-receptor antagonist. |
|---|---|
| Related Catalog | |
| Target |
histamine H2 receptor[1] |
| In Vivo | Niperotidine (piperonyl-ranitidine) is a H2 blocking agent. Niperotidine is a H2-receptor antagonist structurally related to ranitidine. After oral administration, it reaches a plasmatic peak within 60-120 min and is eliminates either in the urine or in the faeces, with an enterohepatic circulation[2]. |
| References |
| Density | 1.268g/cm3 |
|---|---|
| Boiling Point | 566.324ºC at 760 mmHg |
| Molecular Formula | C20H26N4O5S |
| Molecular Weight | 434.50900 |
| Flash Point | 296.302ºC |
| Exact Mass | 434.16200 |
| PSA | 130.02000 |
| LogP | 4.06310 |
| Index of Refraction | 1.591 |
| Storage condition | 2-8℃ |