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Related CAS#:

6536-18-1

6536-18-1 structure
6536-18-1 structure
  • Name: Morazone
  • Chemical Name: 1,5-dimethyl-4-[(3-methyl-2-phenylmorpholin-4-yl)methyl]-2-phenylpyrazol-3-one
  • CAS Number: 6536-18-1
  • Molecular Formula: C23H27N3O2
  • Molecular Weight: 377.47900
  • Create Date: 2018-06-15 12:57:53
  • Modify Date: 2023-01-16 10:35:24
  • Morazone is a nonsteroidal anti-inflammatory drug which is used as an analgesic. It produces phenmetrazine as a major metabolite and has been reported to have been abused as a recreational drug in the past.

Name 1,5-dimethyl-4-[(3-methyl-2-phenylmorpholin-4-yl)methyl]-2-phenylpyrazol-3-one
Synonyms 1,5-dimethyl-4-(3-methyl-2-phenyl-morpholinomethyl)-2-phenyl-1,2-dihydro-pyrazol-3-one
1,5-Dimethyl-4-(3-methyl-2-phenyl-morpholinomethyl)-2-phenyl-1,2-dihydro-pyrazol-3-on
Morazonum [INN-Latin]
R 445
EINECS 229-447-1
Morazone
1,5-dimethyl-4-(3-methyl-2-phenyl-morpholin-4-ylmethyl)-2-phenyl-1,2-dihydro-pyrazol-3-one
Tarugan
Novartrina
Morazona [INN-Spanish]
Orsimon
Density 1.153g/cm3
Boiling Point 503.9ºC at 760 mmHg
Molecular Formula C23H27N3O2
Molecular Weight 377.47900
Flash Point 258.5ºC
Exact Mass 377.21000
PSA 39.40000
LogP 3.38430
Index of Refraction 1.587

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ9200000
CHEMICAL NAME :
3-Pyrazolin-5-one, 2,3-dimethyl-4-(3-methyl-2-phenylmorpholino)methyl-1- phenyl-
CAS REGISTRY NUMBER :
6536-18-1
BEILSTEIN REFERENCE NO. :
0347917
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C23-H27-N3-O2
MOLECULAR WEIGHT :
377.53
WISWESSER LINE NOTATION :
T6N DOTJ B1 CR& A1- DT5NNVJ A1 BR E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 5,346,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 5,346,1965

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6536-18-1 structure

6536-18-1

Literature: Hengen et al. Arzneimittel Forschung, 1958 , vol. 8, p. 421