171178-46-4

171178-46-4 structure

Name: 5-[(tert-butoxycarbonyl)amino]-2-chloroisonicotinic acid
Chemical Name: 2-chloro-5-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine-4-carboxylic acid
CAS Number: 171178-46-4
Molecular Formula: C₁₁H₁₃ClN₂O₄
Molecular Weight: 272.685
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Chloropyridine
Create Date: 2018-06-11 17:05:25
Modify Date: 2025-08-24 16:52:35

Name	2-chloro-5-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine-4-carboxylic acid
Synonyms	4-Pyridinecarboxylic acid, 2-chloro-5-[[(1,1-dimethylethoxy)carbonyl]amino]- 5-[N-(tert-butoxycarbonyl)amino]-2-chloropyridine-4-carboxylic acid 5-Amino-2-chloroisonicotinic acid,5-BOC protected 5-Boc-amino-2-chloropyridine-4-carboxylic acid 5-[(tert-butoxy)carbonylamino]-2-chloropyridine-4-carboxylic acid 2-Chloro-5-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)isonicotinic acid 5-((tert-butoxycarbonyl)amino)-2-chloroisonicotinic acid

Density	1.4±0.1 g/cm3
Boiling Point	420.6±45.0 °C at 760 mmHg
Molecular Formula	C₁₁H₁₃ClN₂O₄
Molecular Weight	272.685
Flash Point	208.2±28.7 °C
Exact Mass	272.056396
PSA	88.52000
LogP	4.38
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.588

Risk Phrases	20/21/22
Safety Phrases	36/37-24/25
HS Code	2933399090

124-38-9

171178-45-3

~68%

171178-46-4

Literature: WARNER-LAMBERT COMPANY LLC Patent: WO2005/16926 A1, 2005 ; Location in patent: Page/Page column 114-115 ; WO 2005/016926 A1

171178-45-3

~57%

171178-46-4

Literature: Warner-Lambert Company Patent: US5654307 A1, 1997 ; US 5654307 A

124-38-9

171178-46-4

Literature: WO2006/24834 A1, ; Page/Page column 74-75 ; WO 2006/024834 A1

110-18-9

171178-45-3

171178-46-4

Literature: EP1171440 B1, ; Page 59 ;

60-29-7

171178-45-3

~34%

171178-46-4

Literature: Gavai, Ashvinikumar V.; Norris, Derek J.; Han, Wen-Ching; Vite, Gregory D.; Fink, Brian E.; Tokarski, John S. Patent: US2005/192310 A1, 2005 ; Location in patent: Page/Page column 28 ;

5326-23-8

171178-46-4

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 11 p. 1401 - 1405

5350-93-6

171178-46-4

Literature: Journal of the Chemical Society - Perkin Transactions 1, , # 18 p. 2221 - 2226

24424-99-5

171178-46-4

Literature: Journal of the Chemical Society - Perkin Transactions 1, , # 18 p. 2221 - 2226

Precursor 7
124-38-9 171178-45-3 110-18-9 60-29-7
5326-23-8 5350-93-6 24424-99-5
DownStream 3
58483-95-7 171178-47-5 305371-42-0

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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