136081-84-0
136081-84-0 structure
- Name: SPIRO[CHROMENE-2,4'-PIPERIDIN]-4(3H)-ONE
- Chemical Name: Spiro[chromene-2,4'-piperidin]-4-(3H)-one
- CAS Number: 136081-84-0
- Molecular Formula: C13H15NO2
- Molecular Weight: 217.26400
- Create Date: 2018-11-25 14:23:58
- Modify Date: 2025-09-11 18:07:04
| Name | Spiro[chromene-2,4'-piperidin]-4-(3H)-one |
|---|---|
| Synonyms | spiro[3H-chromene-2,4'-piperidine]-4-one |
| Density | 1.21g/cm3 |
|---|---|
| Boiling Point | 382.2ºC at 760 mmHg |
| Molecular Formula | C13H15NO2 |
| Molecular Weight | 217.26400 |
| Flash Point | 185ºC |
| Exact Mass | 217.11000 |
| PSA | 38.33000 |
| LogP | 2.10280 |
| Vapour Pressure | 4.79E-06mmHg at 25°C |
| Index of Refraction | 1.594 |
| Hazard Codes | Xn |
|---|---|
| HS Code | 2934999090 |
|
~10%
136081-84-0 |
| Literature: VERTEX PHARMACEUTICALS INCORPORATED; HADIDA-RUAH, Sara, Sabina; MILLER, Mark, Thomas; KALLEL, Edward, Adam; BEAR, Brian, Richard; ARUMUGAM, Vijayalaksmi; DENINNO, Michael, Paul; ZHOU, Jinglan; UY, Johnny; FRIEMAN, Bryan, A. Patent: WO2012/112743 A1, 2012 ; Location in patent: Page/Page column 70 ; |
|
~96%
136081-84-0 |
| Literature: PFIZER PRODUCTS INC. Patent: WO2008/65508 A1, 2008 ; Location in patent: Page/Page column 21 ; |
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~%
136081-84-0 |
| Literature: VERTEX PHARMACEUTICALS INCORPORATED; HADIDA-RUAH, Sara, Sabina; MILLER, Mark, Thomas; KALLEL, Edward, Adam; BEAR, Brian, Richard; ARUMUGAM, Vijayalaksmi; DENINNO, Michael, Paul; ZHOU, Jinglan; UY, Johnny; FRIEMAN, Bryan, A. Patent: WO2012/112743 A1, 2012 ; |
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~%
136081-84-0 |
| Literature: VERTEX PHARMACEUTICALS INCORPORATED; HADIDA-RUAH, Sara, Sabina; MILLER, Mark, Thomas; KALLEL, Edward, Adam; BEAR, Brian, Richard; ARUMUGAM, Vijayalaksmi; DENINNO, Michael, Paul; ZHOU, Jinglan; UY, Johnny; FRIEMAN, Bryan, A. Patent: WO2012/112743 A1, 2012 ; |
|
~%
136081-84-0 |
| Literature: Yang, Lihu; Morriello, Greg; Prendergast, Kristine; Cheng, Kang; Jacks, Tom; Chan, Wanda W.-S.; Schleim, Klaus D.; Smith, Roy G.; Patchett, Arthur A. Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 1 p. 107 - 112 |
|
~%
136081-84-0 |
| Literature: Yang, Lihu; Morriello, Greg; Prendergast, Kristine; Cheng, Kang; Jacks, Tom; Chan, Wanda W.-S.; Schleim, Klaus D.; Smith, Roy G.; Patchett, Arthur A. Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 1 p. 107 - 112 |
| Precursor 6 | |
|---|---|
| DownStream 1 | |
![spiro[3,4-dihydrochromene-2,4'-piperidine]-4-ol structure](https://image.chemsrc.com/caspic/406/935534-37-5.png)
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |