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1859-87-6

1859-87-6 structure
1859-87-6 structure
  • Name: echinuline
  • Chemical Name: echinulin
  • CAS Number: 1859-87-6
  • Molecular Formula: C29H39N3O2
  • Molecular Weight: 461.639
  • Catalog: Natural product Alkaloid
  • Create Date: 2018-03-12 08:00:00
  • Modify Date: 2025-08-21 12:27:49
  • Echinulin (Echinuline) is a cyclic dipeptide carrying a triprenylated indole moiety. Echinulin contributes to the activation of T cell subsets, which leads to NF-κB activation.Echinulin exerts its immune roles by the NF-κB pathway.Echinulin has the potential to serve as a immunotherapeutic agent[1].

Name echinulin
Synonyms (3S,6S)-3-Methyl-6-{[2-(2-methyl-3-buten-2-yl)-5,7-bis(3-methyl-2-buten-1-yl)-1H-indol-3-yl]methyl}-2,5-piperazinedione
(3S,6S)-3-Methyl-6-{[2-(2-methylbut-3-en-2-yl)-5,7-bis(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}piperazine-2,5-dione
2,5-Piperazinedione, 3-[[2-(1,1-dimethyl-2-propen-1-yl)-5,7-bis(3-methyl-2-buten-1-yl)-1H-indol-3-yl]methyl]-6-methyl-, (3S,6S)-
echinuline
(3S-cis)-3-[[2-(1,1-Dimethyl-2-propenyl)-5,7-bis(3-methyl-2-butenyl)-1H-indol-3-yl]methyl]-6-methyl-2,5-piperazinedione
Description Echinulin (Echinuline) is a cyclic dipeptide carrying a triprenylated indole moiety. Echinulin contributes to the activation of T cell subsets, which leads to NF-κB activation.Echinulin exerts its immune roles by the NF-κB pathway.Echinulin has the potential to serve as a immunotherapeutic agent[1].
Related Catalog
Target

NF-κB

References

[1]. Zheng-Fei Yan, et al. Immune activation effects of Eurotium cristatum on T cells through NF-κB signaling pathways in humans.

Density 1.1±0.1 g/cm3
Boiling Point 695.3±55.0 °C at 760 mmHg
Melting Point 242-243°
Molecular Formula C29H39N3O2
Molecular Weight 461.639
Flash Point 374.3±31.5 °C
Exact Mass 461.304230
PSA 73.99000
LogP 5.94
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.566
Hazard Codes Xi
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