Name | albendazole |
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Synonyms |
Carbamic acid, N-[5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester
Methyl hydrogen [6-(propylsulfanyl)-1H-benzimidazol-2-yl]carbonimidate SKF62979 Methanol, 1-methoxy-1-[[6-(propylthio)-1H-benzimidazol-2-yl]imino]-, (E)- Bilutac MFCD00083232 ALBEN Atasol carbamic acid, [5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester SK&F-62979 ZENTEL SK&F 62979 ALBENZA EINECS 259-414-7 methyl-5-propylthio-2-benzimidazole carbamate Bruzol methyl N-[5-(propylthio)-1H-benzimidazol-2-yl]carbamate Albendazole ZEBEN methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate methyl 5-(propylthio)benzimidazol-2-ylcarbamate 5-propylthio-2-carbomethoxyaminobenzimidazole Methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate methyl [5-(propylsulfanyl)-1H-1,3-benzimidazol-2-yl]carbamate Monil SK&F62979 |
Description | Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.Target: AntiparasiticAlbendazole, marketed as Albenza (United States), Eskazole, Zentel, Andazol and Alworm, is a benzimidazole drug used for the treatment of a variety of parasitic worm infestations. Although this use is widespread in the United States, the U.S. Food and Drug Administration (FDA) has not approved albendazole for this indication. It is marketed by Amedra Pharmaceuticals. Albendazole was first discovered at the SmithKline Animal Health Laboratories in 1972. It is a broad spectrum anthelmintic, effective against roundworms, tapeworms, and flukes of domestic animals and humans.Albendazole has been used as an anthelmintic and for control of flukes in a variety of animal species, including cattle, sheep, goats, swine, camels, dogs, cats, elephants, poultry and others. In many countries, it is very commonly used for ruminant livestock. For use in livestock, albendazole is marketed by Zoetis (formerly Pfizer Animal Health) in numerous countries (including the United States and Canada) as Valbazen in oral suspension and paste formulations; by Interchemie in the Netherlands and elsewhere as Albenol-100; by Channelle Animal Health Ltd. in the United Kingdom as Albex; by Ravensdown in New Zealand as Albendazole; etc. Although most formulations are administered orally, Ricomax (ricobendazole, or albendazole sulfoxide) is administered by subcutaneous injection. |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Melting Point | 207-211°C(分解) |
Molecular Formula | C12H15N3O2S |
Molecular Weight | 265.331 |
Exact Mass | 265.088501 |
PSA | 92.31000 |
LogP | 3.07 |
Index of Refraction | 1.634 |
Storage condition | 0-6°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
|
Symbol |
GHS08 |
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Signal Word | Warning |
Hazard Statements | H361-H373 |
Precautionary Statements | P281 |
Target Organs | Blood |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
Hazard Codes | T |
Risk Phrases | R61:May cause harm to the unborn child. R36/37/38:Irritating to eyes, respiratory system and skin . |
Safety Phrases | S53-S45-S37/39-S26 |
RIDADR | NONH for all modes of transport |
WGK Germany | 2 |
RTECS | FD1100000 |
HS Code | 3004909090 |
~% 54965-21-8 |
Literature: SEQUENT SCIENTIFIC LIMITED; Rane, Ramkrishna Appaji; Naithani, Sushil; Natikar, Rajendra Devendra; Verma, Sudhakar; Arulmoli, Thangavel Patent: US2013/303782 A1, 2013 ; Location in patent: Paragraph 0031 ; |
~% 54965-21-8 |
Literature: US4368328 A1, ; |
~30% 54965-21-8 |
Literature: Hazelton; Iddon; Suschitzky; Woolley Tetrahedron, 1995 , vol. 51, # 39 p. 10771 - 10794 |
~% 54965-21-8 |
Literature: WO2012/70069 A2, ; |
~% 54965-21-8 |
Literature: WO2012/70069 A2, ; |
~% 54965-21-8 |
Literature: WO2012/70069 A2, ; |
~43% 54965-21-8 |
Literature: Hazelton; Iddon; Suschitzky; Woolley Tetrahedron, 1995 , vol. 51, # 39 p. 10771 - 10794 |
~29% 54965-21-8 |
Literature: Hazelton; Iddon; Suschitzky; Woolley Tetrahedron, 1995 , vol. 51, # 39 p. 10771 - 10794 |
~% 54965-21-8 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 11 p. 1359 - 1362 |
Precursor 10 | |
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DownStream 2 | |
HS Code | 2933990013 |
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Summary | 2933990013 6-(3,5-dichloro-4-methylphenyl)pyridazin-3(2h)-one。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0% |