112-07-2

DATA ITEMS CITED :

18

MOLECULAR FORMULA :

C8-H16-O3

MOLECULAR WEIGHT :

160.24

WISWESSER LINE NOTATION :

4O2OV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Open irritation test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/31/1966

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,713,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2400 mg/kg

TOXIC EFFECTS :

Kidney, Ureter, Bladder - hematuria Kidney, Ureter, Bladder - other changes in urine composition

REFERENCE :

TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 51,117,1979

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

3200 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

1500 mg/kg

TOXIC EFFECTS :

Kidney, Ureter, Bladder - hematuria Kidney, Ureter, Bladder - other changes in urine composition Blood - normocytic anemia

REFERENCE :

TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 51,117,1979

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

5 mL/kg

REFERENCE :

KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRIA:TWA 20 ppm (135 mg/m3) JAN 1993 OEL-GERMANY:TWA 20 ppm (135 mg/m3);Skin JAN 1993 OEL-THE NETHERLANDS:TWA 20 ppm (135 mg/m3);STEL 40 ppm;Skin JAN 1993 OEL-SWITZERLAND:TWA 20 ppm (135 mg/m3);STEL 40 ppm;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 10 ppm (54 mg/m3);Skin JAN 1993 OEL-UNITED KINGDOM:TWA 5 ppm (24 mg/m3);Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO EGBEA-air:10H TWA 5 ppm (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81350 No. of Facilities: 4676 (estimated) No. of Industries: 50 No. of Occupations: 41 No. of Employees: 36527 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81350 No. of Facilities: 15329 (estimated) No. of Industries: 116 No. of Occupations: 70 No. of Employees: 150893 (estimated) No. of Female Employees: 38379 (estimated)