951135-00-5
951135-00-5 structure
- Name: JNJ-38893777
- Chemical Name: 5H-Pyrimido[4,5-d]azepin-4-amine, 6,7,8,9-tetrahydro-2-(1-piperidinyl)-N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)-2-pyridinyl]
- CAS Number: 951135-00-5
- Molecular Formula: C26H26F6N6
- Molecular Weight: 536.51500
- Create Date: 2016-08-02 11:04:35
- Modify Date: 2024-01-12 09:49:26
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JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain..
| Name | 5H-Pyrimido[4,5-d]azepin-4-amine, 6,7,8,9-tetrahydro-2-(1-piperidinyl)-N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)-2-pyridinyl] |
|---|---|
| Synonyms | [2-(Piperidin-1-yl)-7-(3-trifluoromethylpyridin-2-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-yl](4-trifluoromethylphenyl)amine |
| Density | 1.360±0.06 g/cm3 (20 °C, 760 mmHg) |
|---|---|
| Boiling Point | 627.8±65.0 °C (760 mmHg) |
| Molecular Formula | C26H26F6N6 |
| Molecular Weight | 536.51500 |
| Exact Mass | 536.21200 |
| PSA | 57.18000 |
| LogP | 6.45130 |