381212-03-9

381212-03-9 structure

Name: Pefcalcitol
Chemical Name: 2-[(1S)-1-[(3aS,4E,7aS)-4-[(2Z)-2-[(3S,5R)-3,5-dihydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-1-yl]ethoxy]-N-(2,2,3,3,3-pentafluoropropyl)acetamide
CAS Number: 381212-03-9
Molecular Formula: C₂₆H₃₄F₅NO₄
Molecular Weight: 519.544
Catalog: Research Areas Inflammation/Immunology
Create Date: 2017-09-19 15:48:49
Modify Date: 2025-08-24 23:14:38
Pefcalcitol is a new antipsoriatic antedrug candidates having 16-en-22-oxa-vitamin D3 structures.

Name	2-[(1S)-1-[(3aS,4E,7aS)-4-[(2Z)-2-[(3S,5R)-3,5-dihydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-1-yl]ethoxy]-N-(2,2,3,3,3-pentafluoropropyl)acetamide
Synonyms	2-{[(1S,3R,5Z,7E,9ξ,20S)-1,3-Dihydroxy-9,10-secopregna-5,7,10,16-tetraen-20-yl]oxy}-N-(2,2,3,3,3-pentafluoropropyl)acetamide M5181 Pefcalcitol 2-(((1S,3R,5z,7E,20S)-1,3-dihydroxy-9,10-secopregna-5,7,10(19),16-tetraen-20-yl)oxy)-N-(2,2,3,3,3-pentafluoropropyl)acetamide UNII-KT5224XSHW Acetamide,2-((1S)-1-((3aS,7E,7as)-7-((2Z)-((3S,5R)-3,5-dihydroxy-2-methylenecyclohexylidene)ethylidene)-3a,4,5,6,7,7a-hexahydro-3a-methyl-1H-inden-3-yl)ethoxy)-N-(2,2,3,3,3-pentafluoropropyl) Acetamide, 2-[(1S)-1-[(3aS,7E,7aS)-7-[(2Z)-2-[(3S,5R)-3,5-dihydroxy-2-methylenecyclohexylidene]ethylidene]-3a,4,5,6,7,7a-hexahydro-3a-methyl-1H-inden-3-yl]ethoxy]-N-(2,2,3,3,3-pentafluoropropyl)- Pefcalcitol [INN]

Description	Pefcalcitol is a new antipsoriatic antedrug candidates having 16-en-22-oxa-vitamin D3 structures.
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Akira Takeiri, Kenji Tanaka. et al. Lack of Mutagenicity of SMD-502, a New Vitamin D3 Analog for Topical Application, in Skin and Liver of gpt delta Transgenic Mice and in GDL1 Cells. Genes and Encironment, Vol, 34, No. 3 pp. 107-114(2012)