403646-00-4

403646-00-4 structure

Name: TMC-205
Chemical Name: 6-(3-methylbuta-1,3-dienyl)-1H-indole-3-carboxylic acid
CAS Number: 403646-00-4
Molecular Formula: C₁₄H₁₃NO₂
Molecular Weight: 227.25900
Create Date: 2017-01-29 16:15:36
Modify Date: 2025-09-18 15:56:51
TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter[1].

Name	6-(3-methylbuta-1,3-dienyl)-1H-indole-3-carboxylic acid
Synonyms	1H-Indole-3-carboxylic acid,6-[(1E)-3-methyl-1,3-butadienyl]

Description	TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter[1].
Related Catalog	Research Areas >> Cancer
Target	Microbial Metabolite
References	[1]. Gao Y, et al. Total Synthesis and Biological Studies of TMC-205 and Analogues as Anticancer Agents and Activators of SV40 Promoter. ACS Med Chem Lett. 2014;5(8):863-867. Published 2014 Jun 23.