179388-54-6

179388-54-6 structure

Name: macrocarpal I
Chemical Name: 5-[1-[(1S,4R,4aR,6R,8aS)-4-hydroxy-6-(2-hydroxypropan-2-yl)-4,8a-dimethyl-1,2,3,4a,5,6,7,8-octahydronaphthalen-1-yl]-3-methylbutyl]-2,4,6-trihydroxybenzene-1,3-dicarbaldehyde
CAS Number: 179388-54-6
Molecular Formula: C₂₈H₄₂O₇
Molecular Weight: 490.63
Catalog: Natural product Sesquiter
Create Date: 2016-07-08 06:07:51
Modify Date: 2025-08-29 15:23:53
Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC50 value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni[1].

Name	5-[1-[(1S,4R,4aR,6R,8aS)-4-hydroxy-6-(2-hydroxypropan-2-yl)-4,8a-dimethyl-1,2,3,4a,5,6,7,8-octahydronaphthalen-1-yl]-3-methylbutyl]-2,4,6-trihydroxybenzene-1,3-dicarbaldehyde
Synonyms	1,3-Benzenedicarboxaldehyde, 5-[(1R)-1-[(1S,4R,4aR,6R,8aS)-decahydro-4-hydroxy-6-(1-hydroxy-1-methylethyl)-4,8a-dimethyl-1-naphthalenyl]-3-methylbutyl]-2,4,6-trihydroxy- 1,3-Benzenedicarboxaldehyde, 5-((1R)-1-((1S,4R,4aR,6R,8aS)-decahydro-4-hydroxy-6-(1-hydroxy-1-methylethyl)-4,8a-dimethyl-1-naphthalenyl)-3-methylbutyl)-2,4,6-trihydroxy- 2,4,6-Trihydroxy-5-{(1R)-1-[(1S,4R,4aR,6R,8aS)-4-hydroxy-6-(2-hydroxy-2-propanyl)-4,8a-dimethyldecahydro-1-naphthalenyl]-3-methylbutyl}isophthalaldehyde

Description	Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC50 value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Tian L W, et al. Eucalmaidials A and B, phloroglucinol-coupled sesquiterpenoids from the juvenile leaves of Eucalyptus maideni[J]. RSC Advances, 2014, 4(41): 21373-21378.

Hazard Codes	Xi