65189-64-2
65189-64-2 structure
- Name: (D-Ala2)-Leu-Enkephalin amide
- Chemical Name: (2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
- CAS Number: 65189-64-2
- Molecular Formula: C29H40N6O6
- Molecular Weight: 568.66400
- Catalog: Research Areas Neurological Disease
- Create Date: 2018-06-22 17:51:09
- Modify Date: 2025-08-25 22:42:20
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[D-Ala2] Leu-Enkephalinamide is an enkephalin analog. [D-Ala2] Leu-Enkephalinamide has great corneal permeability and analgesic effect. [D-Ala2] Leu-Enkephalinamide can be used for the research of ocular diseases[1][2].
| Name | (2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide |
|---|---|
| Synonyms |
Leu-enkephalinamide,ala(2)
enkephalinamide-Leu,Ala(2) 2-Ala-leu-enkephalinamide Enkephalinamide-leu,alanine(2) DALEA Leucine-enkephalinamide,ala(2) DALE (D-Ala2)-Leu-Enkephalin amide Ala(2)-Enkephalinamide-Leu |
| Description | [D-Ala2] Leu-Enkephalinamide is an enkephalin analog. [D-Ala2] Leu-Enkephalinamide has great corneal permeability and analgesic effect. [D-Ala2] Leu-Enkephalinamide can be used for the research of ocular diseases[1][2]. |
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| Related Catalog | |
| In Vitro | [D-Ala2] Leu-Enkephalinamide (MEA) (1.0 mM; 10-240 min) has great corneal permeability in vitro[1]. |
| In Vivo | D-Ala2-Leu-enkephalinamide (s.c.) is also enhanced in morphine-dependent animals[2]. |
| Molecular Formula | C29H40N6O6 |
|---|---|
| Molecular Weight | 568.66400 |
| Exact Mass | 568.30100 |
| PSA | 220.69000 |
| LogP | 4.83780 |